Ursodeoxycholic acid | Ursosan® Forte| Урсосан® Форте – liver and gallbladder support, hepatoprotector when impaired liver function.
New form designed specifically for the convenience of patients in need of high doses of ursodeoxycholic acid.
It has a immunomodulating, hypocholesterolemic, hypolipidemic, cholelitolytic, choleretic, hepatoprotective effect.
Ursodeoxycholic acid is integrated into the membrane of the hepatocyte, cholangiocyte and gastrointestinal epithelial cell, stabilizes its structure and protects the cell from the damaging effects of toxic bile salts, thereby reducing their cytotoxic effect.
Reduces the saturation of bile with cholesterol due to inhibition of its absorption in the intestine, suppression of synthesis in the liver and lower secretion in bile; contributes to the gradual breakdown of cholesterol gallstones, which is achieved mainly due to the dispersion of cholesterol and the formation of liquid crystals; reduces the lithogenic index of bile, increases the concentration of bile acids in it. The result is the dissolution of cholesterol gallstones and the prevention of the formation of new calculi.
It causes an increase in gastric and pancreatic secretion, enhances lipase activity, has a hypoglycemic effect.
The immunomodulatory effect of ursodeoxycholic acid is due to normalization of the natural killer activity of lymphocytes.
Indications for use
- uncomplicated gallstone disease: biliary sludge; dissolution of cholesterol gallstones with a functioning gallbladder;
prevention of recurrence of stone formation after cholecystectomy;
- chronic hepatitis of various origins (including toxic, medicinal);
- cholestatic diseases of the liver of various origins, including primary biliary cirrhosis (in the absence of signs of decompensation), primary sclerosing cholangitis, cystic fibrosis (cystic fibrosis);
- non-alcoholic fatty liver disease, including non-alcoholic steatohepatitis;
- alcoholic liver disease;
- chronic viral hepatitis;
- biliary dyskinesia;
- biliary reflux gastritis and reflux esophagitis.
